The proportion of patients who experienced any adverse event was 21 percent among those getting low-dose radioiodine versus 33 percent among those receiving high-dosage radioiodine , with rates of neck discomfort and nausea favoring the low-dosage group. Rates of adverse events were similar in the thyrotropin alfa group and the group undergoing thyroid hormone withdrawal, though there was a pattern favoring the thyrotropin alfa group . Three months after ablation, the prices of adverse events were 27 percent in the low-dose group versus 24 percent in the high-dosage group and 27 percent in the thyrotropin alfa group versus 24 percent in the group undergoing thyroid hormone withdrawal .Every one of these volunteers and their communities made a significant contribution to HIV prevention research, Warren stated. As we move forward in our search for new HIV prevention choices, researchers will need the aid of thousands more volunteers around the world. We hope that lots of more communities and individuals will observe in the footsteps of the MDP 301 trial participants. While this trial did not result in an effective product, it had been a successful trial – it provided a clear result, if that result is disappointing even. In many ways, this trial should serve as a model for future HIV prevention trials as it provides critical scientific information in addition to essential lessons from the extensive social science element and the extensive community engagement and planning undertaken by the trial staff.